BOC Blood Bank Practice Exam

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Given anti-C: +, anti-D: +, anti-E: +, anti-c: +, anti-e: +, what is the most probable genotype?

R1R1

R1r'

R0r"

R1R2

The most probable genotype reflected by the Rh typing results of anti-C: +, anti-D: +, anti-E: +, anti-c: +, and anti-e: + involves the presence of multiple specific antigens.

The positive reactions indicate that the individual expresses multiple Rh antigens, including C, D, E, c, and e. In blood group genetics, the R1R2 genotype represents one allele that can contribute to these positive reactions. Specifically, R1 corresponds to the D and E antigens while R2 correlates with the c and E antigens. The combination of anti-C and anti-c positivity also indicates that the person possesses both the C and c antigens, further supported by the presence of anti-E and anti-e indicating the presence of both E and e.

This means that the genotype must incorporate both the R1 allele, which expresses D and possibly C, and the R2 allele, which expresses E and c. Thus, the genotype R1R2 encompasses all these antigens noted by the positivity of the corresponding antisera.

The other genotypes like R1R1 or R0r" do not account for the presence of all these antigens as observed in the reaction pattern. In summary,

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