A patient with A2B, Rh-positive blood has anti-A1 antibodies. Which blood type should be chosen for crossmatching?

In selecting the appropriate blood type for crossmatching in a patient with A2B, Rh-positive blood who has anti-A1 antibodies, it is essential to consider compatibility based on the antigen-antibody interaction. The patient in question is A2B, meaning they express the A antigen (specifically the A2 type) and the B antigen on their red blood cells. However, they have anti-A1 antibodies, which react against the A1 antigen found on A1 and A1B blood types.

Choosing blood from a B group (whether Rh-positive or Rh-negative) means that the donor blood will not have A antigens, making it compatible since there won’t be an A1 antigen to react with the patient's anti-A1 antibodies. This leads to avoiding any adverse reactions during transfusion. Rh-positive blood can be given to Rh-positive patients without concern, thereby making B Rh-positive a suitable option.

The other choices—B Rh-negative, A1B Rh-positive, and O Rh-negative—present complications. While B Rh-negative may also be compatible, the chosen option explicitly mentions Rh-positive blood, which aligns directly with the patient's Rh status. A1B Rh-positive would pose a risk due to the presence of A1 antigens,