Cryoprecipitated AHF is typically derived from which blood component?

Cryoprecipitated AHF, or cryoprecipitate antihemophilic factor, is derived from plasma. When fresh frozen plasma (FFP) is frozen, the fibrinogen and some other clotting factors (specifically factor VIII, von Willebrand factor, and factor XIII) precipitate when the plasma is thawed. This precipitate is rich in these clotting factors and is collected to be used in clinical situations, particularly in managing patients with bleeding disorders like hemophilia.

While whole blood contains plasma, red blood cells, and platelets, cryoprecipitate specifically targets and isolates the factors that are most beneficial for treating conditions related to deficiencies in fibrinogen and factor VIII. Additionally, red blood cells and platelets are not the sources of cryoprecipitate, as they do not provide the necessary clotting factors.