Fresh Frozen Plasma from a group A, Rh-positive donor may be safely transfused to a patient who is which blood group?

Fresh Frozen Plasma (FFP) transfusions prioritize the compatibility of the donor's plasma with the recipient's blood type, particularly with respect to the ABO blood group system as well as the Rh factor. The correct answer reflects compatibility based on the presence of antibodies in the donor's plasma.

In this case, Fresh Frozen Plasma from a group A, Rh-positive donor contains anti-B antibodies. Patients who receive FFP need to be compatible with the antibodies present in the donor plasma. Group A plasma contains anti-B antibodies, meaning that it can be transfused safely to a patient who is a group A or AB, since these groups do not have B antigens that would elicit an immune response.

Transfusing to a patient who is group A, even if Rh-negative, is appropriate because the absence of B antigens in the recipient means there are no antibodies that would react with the plasma being transfused. The Rh status also matters, but FFP can generally be given as long as the primary ABO compatibility is maintained. In this case, the Rh-negative recipient will not have problems as the plasma does not contribute to any significant Rh antigen-related concerns.

While the Rh positivity of the donor is important in red cell transfusions (where Rh-negative patients