The preservation of platelets during storage is primarily affected by what factor?

The preservation of platelets during storage is primarily influenced by pH levels. Platelets have a specific pH range in which they remain viable and functional. During storage, the metabolic processes of platelets can lead to the production of lactic acid, which can lower the pH of the storage medium. If the pH drops below the optimal level, it can negatively impact platelet function and survival. Maintaining an appropriate pH is crucial because it helps preserve platelet activation responses and overall functionality.

While temperature control is also important for preserving platelets, it primarily affects the metabolic rate rather than the direct biochemical environment that influences platelet viability. Similarly, oxygen levels and the presence of anticoagulants are relevant to storage conditions but do not have the same significant impact on platelet function as pH does. Adjusting the storage environment to ensure ideal pH levels is essential for maintaining the quality of stored platelets.