What is the minimum pH required for Platelets at the end of the storage period according to AABB standards?

The AABB (American Association of Blood Banks) sets specific standards for the storage of blood components to ensure their safety and effectiveness. For platelets, the minimum pH requirement at the end of their storage period is set at 6.2. This level is critical because pH can impact the viability and functionality of platelets. A pH lower than this threshold may indicate metabolic byproducts accumulating during storage, which can lead to compromised platelet function and reduced efficacy when transfused into patients.

Maintaining a pH at or above this standard helps ensure that the platelets retain their functionality and are able to perform their role in hemostasis effectively once transfused. Therefore, a final pH of 6.2 or higher is necessary to ensure the quality and safety of the platelet product for clinical use. This standard reflects the physiological conditions under which platelets operate optimally and is integral to blood banking practices aimed at patient safety.