What is the primary purpose of using leukocyte-reduced red blood cells?

The primary purpose of using leukocyte-reduced red blood cells is to reduce the risk of transfusion reactions. Leukocyte-reduction involves the removal of white blood cells from the blood product, which minimizes the likelihood of febrile non-hemolytic transfusion reactions that can occur due to the recipient's immune response to donor white cells. Additionally, reducing leukocytes helps to decrease the risk of alloimmunization, where the recipient's immune system produces antibodies against the white blood cells, which can complicate future transfusions.

Furthermore, it can lower the risk of transmission of certain infections and also diminish the chances of transfusion-related acute lung injury (TRALI). While the other options regarding improving oxygen-carrying capacity, extending shelf life, and preventing iron overload are relevant to blood transfusion practices, they do not specifically pertain to the primary rationale behind leukocyte reduction in red blood cells.