What test indicates a history of infectious disease that results in deferral from donation?

Hepatitis testing indicates a history of infectious disease that results in deferral from donation because certain types of hepatitis, such as Hepatitis B and Hepatitis C, can lead to long-term health complications and are transmissible through blood. Within blood bank practices, individuals who test positive for these viruses are typically deferred from donating due to the potential risk they pose to recipients.

While HIV, syphilis, and West Nile Virus testing are also critical components of donor screening, they do not have the same level of impact or common presence as hepatitis in terms of deferral based on historical infection. Hepatitis remains a significant concern in transfusion medicine due to its prevalence and the serious health consequences associated with it. Thus, a positive result in hepatitis testing implies a need for deferral from donation to ensure the safety of the patient population relying on transfusions.