What type of blood should be available for a possible exchange transfusion for an infant whose mother is B, Rh-negative with a titer of anti-D?

In the context of preparing for a possible exchange transfusion for an infant whose mother is B, Rh-negative with a titer of anti-D, the most appropriate blood type to consider is O, Rh-negative. This choice is based on several critical factors related to blood compatibility and safety.

Firstly, the infant needs a blood type that is universally acceptable in terms of red blood cell transfusions. Type O blood is considered the universal donor for red cells because it lacks A and B antigens. This property is crucial in avoiding potential hemolytic reactions, particularly in circumstances where the mother’s sensitization against the D antigen could lead to complications if Rh-positive blood were to be transfused.

Secondly, since the mother is Rh-negative, there is a significant risk of Rh incompatibility if Rh-positive blood is used in the exchange transfusion. If Rh-positive blood were to be administered, any residual anti-D antibodies present from the mother's bloodstream could target the Rh-positive red blood cells, leading to hemolysis. Using O, Rh-negative blood circumvents this problem entirely because it will not only not have A or B antigens but also lacks the Rh factor, thereby providing a safe option for the infant.

Therefore, the selection of O, Rh-negative blood