What type of control can AHG (Coombs) control cells be used for?

AHG (Anti-Human Globulin) control cells serve a crucial role in the blood banking process, particularly in ensuring the reliability of tests that involve antiglobulin reactions. The correct response highlights that these control cells are coated only with IgG antibody.

Using AHG control cells that are specifically coated with IgG is essential because the primary purpose of these controls is to verify that the AHG reagent is functioning properly in detecting the presence of IgG antibodies in a patient's serum or on red blood cells. The specificity to IgG is important since the tests, such as indirect or direct antiglobulin tests, primarily seek to identify IgG-mediated sensitization of red blood cells.

In this context, while other choices may present relevant information, they do not accurately represent the specific application or characteristic of AHG control cells. For example, controls for anti-C3 reagents or confirming all positive antiglobulin reactions may involve different types of controls or mixed antibody types (such as IgM), which do not align with the distinct application of IgG-coated AHG control cells. Moreover, stating that it is only for indirect antiglobulin tests limits its use, as these cells can be relevant in other situations where IgG detection is pertinent. Thus