Which antigen shows enhanced reactions with its corresponding antibody after treatment with proteolytic enzymes?

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The enhancement of antigen-antibody reactions following treatment with proteolytic enzymes is an important concept in blood banking, particularly in relation to individual blood group antigens. In this scenario, the antigen that shows enhanced reactions after treatment is the E antigen.

Proteolytic enzymes, such as trypsin or bromelin, can cleave glycoproteins and can affect the structure of cell membranes, consequently modifying the expression of certain antigens. When observing the potentiation of antigen-antibody reactions, particularly with E antigen, it's noted that the treatment removes some of the surrounding carbohydrates or proteins that may otherwise hinder antibody binding, thereby revealing more epitopes or making them more accessible.

The E antigen belongs to the Rh blood group system and often shows increased reactivity with its corresponding antibodies when treated with such enzymes. This characteristic assists in better detection and identification of blood group antigens in serological testing, making it easier to confirm blood types or identify compatible donors.

The other antigens listed may not show the same level of enhancement or even may have diminished reactions depending on their structural characteristics and the nature of the enzymes used. Thus, the reaction enhancement observed specifically with the E antigen after enzyme treatment is what confirms it as the correct answer.

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