Which type of plasma is typically avoided in patients undergoing transfusions due to risks associated with immunological reactions?

In the context of blood transfusions, fresh frozen plasma typically contains all the clotting factors and proteins necessary for coagulation. However, it also retains antibodies that can provoke immunological reactions in recipients, especially if they are of a different blood type. This risk is primarily due to the presence of antibodies against minor blood group antigens that can lead to transfusion-related complications, such as febrile non-hemolytic transfusion reactions or more severe forms of hemolytic reactions.

Avoidance of fresh frozen plasma is often due to concerns about these complications in patients who may have been previously sensitized to certain antigens or have a history of reactions. In contrast, other types of plasma mentioned, like stored plasma and platelet-rich plasma, do not carry the same level of inherent immunological risk to the same extent as fresh frozen plasma. Group-specific plasma is specifically matched to the recipient's blood group to reduce the risk of adverse reactions.